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Pro Pigskin Pick'em is a Facebook application that lets you pick NFL games against the spread and compete with other players that have also added the application. You can create a group and run your own Pick'em pool and compete with a smaller group of friends as well.
As with most sports games of this nature, you play to win prizes. And this football season, Pro Pigskin Pick'em is giving away a $5,000 grand prize along with other weekly prizes to top-scoring players. In order to participate for this grand prize, you'll need to join the company's Facebook group so that your picks can appear on the leader board.