The show will be called Dwaynebook, and it will star stand-up comedian Dwayne Perkins (pictured right), who did a half-hour special for Comedy Central back in 2003. You can see pictures and listen to clips of his stand-up routines for free at his website.
Perkins's manager Matt Schuler (he's also sharing executive production duties) compares the show to green-screen talk shows like The Soup and Tosh.0.
Dwaynebook will also have sketches featuring regular characters who are fictional staff members of the show. We're reminded of The Daily Show's stable of fake correspondents, but they won't all be reporters; one character will be "a sexy research assistant who was hired because of her looks and makes the rest of the show's staff nervous," according to The Wrap.