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Haring was born in Reading, Pennsylvania on May 4, 1958. His father was a cartoonist, and Keith was interested in art from an early age. He studied art at The Ivy School of Professional Art in Pittsburgh, and he later moved to New York City, continuing his studies at the School of Visual Arts.
Just like fellow artist and friend Jean-Michel Basquiat, Haring was inspired by graffiti art. He often collaborated with musicians: he painted Madonna's jacket for a performance of her song "Like a Virgin," and the body of Grace Jones for her music video "I'm Not Perfect."
Haring died on February 16, 1990 from complications due to AIDS. He was only 31 years old.