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It's happening across the country and is organized entirely using Twitter. At each local Tweet-up, participants are asked to donate a new toy or new article of clothing in exchange for an evening of networking and holiday cheer.
If you can't attend a Holiday Tweet Drive, or if there's not an event in your city and you still want to help, find out more @TweetDrive2010 or donate to a local Toys for Tots drop-off point.
If none of this appeals to you, there are hundreds of other ways to do good with social media this holiday season. The easiest we've seen is this Google Chrome browser extension that automatically spurs Google to donate to one of five charities of your choice, the amount accumulating with each additional tab you open.