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MyGoya just launched the US version of its complete web desktop.
Based in Germany, MyGoya is an immersive Flash-based alternative to using your regular desktop - essentially a mini operating system on the web. Once signed up, you get access to a file manager, online storage, an automated workflow application, aggregated email (email from any provider), contact management, a calendar, chat, a media player, bookmarks, notetaking, Flickr search and more. It's nicely designed with draggable windows and tabs, with a resemblance to Windows Vista in some places. Certainly fun to try.