Julie Chen is leaving 'The Talk' following husband Les Moonves' departure from CBS

Julie Chen is leaving CBS' The Talk, just a week after her husband Les Moonves stepped down as head of the company following multiple sexual harassment and assault allegations.

According to CNN, two sources close to Chen said she will be leaving the panel chat show "effective immediately."

The panelist, who took time off from the show immediately following the allegations, will make the announcement in a pre-recorded message to air on Tuesday's episode.

"She has decided that her main focus needs to be clearing her husband’s name from accusations made 25-30 years ago and tending to her son," a source told CNN.

CBS confirmed Chen's departure from the show to Mashable.

"For eight seasons, Julie Chen has co-hosted The Talk with incredible energy, grace and professionalism. Her talents played a big role in our successful launch of CBS’ first network daytime talk show, and in the series growth into an Emmy Award-winning broadcast," read a statement.

"All of us here have tremendous appreciation for the dedication and passion she brought to the show every day and for her generous role as an ambassador for CBS Daytime. We are grateful for her many other contributions, respect her decision and wish Julie all the best in everything she does.”

Chen will reportedly continue to host CBS' Big Brother. The TV host has publicly supported her husband since multiple women came forward to The New Yorker's Ronan Farrow with accusations of sexual abuse against Moonves in July and September.

“I have known my husband, Leslie Moonves, since the late ’90s, and I have been married to him for almost 14 years," she wrote on Twitter in July.

"Leslie is a good man and a loving father, devoted husband and inspiring corporate leader. He has always been a kind, decent and moral human being. I fully support my husband and stand behind him and his statement."

UPDATE: Sept. 19, 2018, 10:26 a.m. AEST Updated with comment from CBS.