Scientists create 'vagina on a chip' for research

It can help study infections like BV.
 By 
Anna Iovine
 on 
white person holding model of the uterus
Vaginal microbiome is much different in humans than in lab animals. Credit: AndreyPopov / Getty Images

Scientists at the Wyss Institute at Harvard University have created a "vagina on a chip" to further research the vaginal microbiome, diseases, and potential drugs.

The vaginal microbiome is a complex bacterial ecosystem that's unique to everyone, board-certified OB/GYN Monte Swarup, MD previously told Mashable. Changes in the microbiome can occur due to age or hormone fluctuations, and sometimes those changes can result in infections. A couple of common issues that can occur are bacterial vaginosis (BV) and vulvovaginal candidiasis, also known as yeast infections.

BV can be treated with antibiotics, but reinfections are common. The condition can lead to more serious complications like pelvic inflammatory disease. If left untreated, it also doubles the risks of STIs and increases the risk of pre-term birth in pregnant people. If you're concerned about BV or any other vaginal infection, go see your doctor; at-home vaginal microbiome tests may not be reliable.


You May Also Like

Hookup apps for everyone

AdultFriendFinder readers’ pick for casual connections

Hinge popular choice for regular meetups

Products available for purchase through affiliate links. If you buy something through links on our site, Mashable may earn an affiliate commission.

As reported in Scientific American, the human microbiome is much different than that of lab animals, so vaginal health is difficult to study in a laboratory. That's why scientists crafted the "vagina on a chip" — in order to have a model of the human microbiome in a lab setting. The chip contains human vaginal tissue from donors, as described in a paper published by the scientific journal Microbiome.

This isn't the first organ to be "chipped" in order to be studied; ones of lungs and intestines have also been created, according to Scientific American. While chips have their limitations — as they exist outside an actual body, with many more organs and bacteria — they have the potential to push research forward. As it is, the vaginal microbiome and infections are understudied, the New York Times reported. Aside from the logistical laboratory reasons, researchers cited a lack of funding for this. Perhaps the "vagina chip" is the first step in changing that.

Topics Health

anna iovine, a white woman with curly chin-length brown hair, smiles at the camera
Anna Iovine
Associate Editor, Features

Anna Iovine is the associate editor of features at Mashable. Previously, as the sex and relationships reporter, she covered topics ranging from dating apps to pelvic pain. Before Mashable, Anna was a social editor at VICE and freelanced for publications such as Slate and the Columbia Journalism Review. Follow her on Bluesky.

Mashable Potato

Recommended For You
This Apple MacBook Air with an M4 chip is $200 off right now
macbook air m4 chip-deal

The iPad Air is finally getting the M4 chip: Preorder now
The new Apple iPad Air with M4 chip

Apple iPhone 17e hands-on: New chip, more storage memory, and yes, MagSafe
Apple iPhone 17e



More in Life
How to watch Chelsea vs. Port Vale online for free
Alejandro Garnacho of Chelsea reacts

How to watch 'Wuthering Heights' at home: Margot Robbie and Jacob Elordi's controversial romance now streaming
Margot Robbie and Jacob Elordi embracing in still from "Wuthering Heights"

How to watch New York Islanders vs. Philadelphia Flyers online for free
Matthew Schaefer of the New York Islanders warms up

How to watch Mexico vs. Belgium online for free
Israel Reyes of Mexico reacts

How to watch Brazil vs. Croatia online for free
Vinicius Junior #10 of Brazil leaves

Trending on Mashable
NYT Connections hints today: Clues, answers for April 3, 2026
Connections game on a smartphone

NYT Connections hints today: Clues, answers for April 4, 2026
Connections game on a smartphone

Wordle today: Answer, hints for April 4, 2026
Wordle game on a smartphone

Wordle today: Answer, hints for April 3, 2026
Wordle game on a smartphone

Google launches Gemma 4, a new open-source model: How to try it
Google Gemma
The biggest stories of the day delivered to your inbox.
These newsletters may contain advertising, deals, or affiliate links. By clicking Subscribe, you confirm you are 16+ and agree to our Terms of Use and Privacy Policy.
Thanks for signing up. See you at your inbox!